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tapi 2

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  • Inhibitors & Agonists
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TAPI 2
TP2108689284-12-6
ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes.
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TNF Protease Inhibitor 2
TAPI-2
TQ0129187034-31-7
TAPI-2 is a broad-spectrum inhibitor of MMP (IC50: 20 μM), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM).
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