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tankyrase1/2

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  • Inhibitors & Agonists
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E7449
Stenoparib, UNII-9X5A2QIA7C
T44711140964-99-3
E7449 (UNII-9X5A2QIA7C) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ~50 and ~50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
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G244-LM
T89641563007-08-8
G244-LM, a potent and specific inhibitor of tankyrase 1 2, effectively inhibits Wnt signaling.
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