tamoxifen citrate

Tamoxifen Citrate is an orally active selective estrogen receptor modulator (SERM) that blocks estrogen activity in breast cells while activating estrogen signaling in cells such as those of the bone, liver, and uterus. As an Hsp90 activator, it enhances the ATPase activity of the Hsp90 chaperone complex, induces autophagy and apoptosis, and can be used to generate gene knockout models in CreER(T2) transgenic mice as well as liver injury models.

Tamoxifen citrate (Standard) is the standard substance of Tamoxifen citrate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tamoxifen Citrate is an orally active selective estrogen receptor modulator (SERM) that blocks estrogen activity in breast cells while activating estrogen signaling in cells such as those of the bone, liver, and uterus. As an Hsp90 activator, it enhances the ATPase activity of the Hsp90 chaperone complex, induces autophagy and apoptosis, and can be used to generate gene knockout models in CreER(T2) transgenic mice as well as liver injury models.

Tamoxifen-d3 hydrochloride is a deuterium-labeled derivative of Tamoxifen (Citrate), which is an orally active selective estrogen receptor modulator (SERM). It inhibits estrogen activity in breast cells while activating estrogen receptors in other cells such as those in bone, liver, and uterus. Tamoxifen Citrate acts as a potent Hsp90 activator, enhancing the ATPase activity of the Hsp90 molecular chaperone. Furthermore, it effectively suppresses infectious EBOV Zaire and Marburg (MARV) viruses with IC50 values of 0.1 μM and 1.8 μM, respectively. Tamoxifen Citrate also stimulates autophagy and induces apoptosis, and is capable of triggering gene knockout in CreER(T2) transgenic mice.