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(1)
By Target- HIF
- HIF/HIF Prolyl-Hydroxylase(1)
- VEGFR(1)
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Results for "
svegfr-1
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Recombinant Protein3
AKB-6899
AKB6899
T297971007377-55-0In house
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth.
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