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Results for "
sulfo-ara-f-nmn
" in TargetMol Product Catalog- Inhibitors & Agonists1
Sulfo-ara-F-NMN
CZ-48
T139071374663-29-2In house
Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NMN to Z-48 or NMN, which has a higher cyclase activity, causes conformational changes in SARM1, resulting in cADPR production, NAD depletion, and non-apoptotic cell death.
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