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STAT6-IN-9
T2105123092076-15-5
STAT6-IN-9 is a highly potent STAT6 inhibitor with an EC₅₀ of 4 nM. It markedly blocks STAT6 activation mediated by the IL-13/IL-13 receptor/IL-4 receptor pathway and inhibits CCL17 secretion with an IC₅₀ of 4.6 nM. STAT6-IN-9 is suitable for studying various chronic inflammatory diseases related to the STAT6 signaling pathway, including allergic diseases, asthma, and chronic obstructive pulmonary disease.
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