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sobetirome

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Sobetirome
IACS-010759, GC1, QRX-431, GC-1, GC 1
T5313211110-63-3
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
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Sob-AM2
T2005942128258-47-7
Sob-AM2 is an effective substrate targeting the fatty acid amide hydrolase (FAAH) expressed in the brain, with a Km of 1.3 μM. It delivers higher concentrations of Sobetirome to the central nervous system at minimal peripheral systemic doses, thereby activating the central thyroid hormone receptor β (TRβ).
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10-14 weeks
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