silodosin

Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.

Silodosin carboxylic acid impurity (KMD-3293) is an inactive metabolite of silodosin. As its primary metabolite, it forms through the oxidation via alcohol and aldehyde dehydrogenases. Silodosin carboxylic acid impurity is utilized in research related to benign prostatic hyperplasia.

Dehydro silodosin (KMD-3241) is a selective α1A-adrenoceptor antagonist applicable in research on benign prostatic hyperplasia.

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate is a natural product that can be used as reference standards.

Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to rats with an LD50 value of 0.347 mg/kg.