sbp 1

High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport mechanisms. Treatments based on antagonists specifically targeting extracellular HMGB1 have generated encouraging results in a wide number of experimental models of infectious and sterile inflammation.

HMGB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.5 kDa and the accession number is A0A024RDR0.

HMGB1 Protein, Human, Recombinant (aa 1-215, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is A0A024RDR0.

HMGB1 Protein, Human, Recombinant (aa 57-158, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 13.6 kDa and the accession number is P09429.

Expression system: HEK293 Cells
Length: 1-215, Full Length
Activity: Not Tested