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(2)
By Target- GSK-3
- Autophagy(1)
- PROTACs(1)
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Results for "
sb 216763
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- PROTAC Products1
- SB 216763SB216763T3077280744-09-4SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).
- $33
SizeQTY
Cited - PROTAC GSK-3β Degrader-1T209446PROTACGSK-3β Degrader-1 (compound 1) is a degrader targeting GSK-3β with an IC50 of 833 nM. This compound consists of SB-216763 (a GSK-3β inhibitor), a PEG linker, and CRBN (E3 ligase ligand). It reduces neurotoxicity induced by Aβ25-35 peptide and CuSO4 and is applicable in Alzheimer's disease research.
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