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sartorypyrone d

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Sartorypyrone D
T368751801167-48-5
Sartorypyrone D is a fungal metabolite that has been found inN. fischeri.1It inhibits NADH fumarate reductase (NFRD; IC50= 1.7 μM inA. suummitochondria) and NADH oxidase (IC50= 3 μM in bovine heart mitochondria). Sartorypyrone is active against the Gram-positive bacteriaB. subtilis,K. rhizophila, andM. smegmatisin disc assays. 1.Kaifuchi, S., Mori, M., Nonaka, K., et al.Sartorypyrone D: A new NADH-fumarate reductase inhibitor produced by Neosartorya fischeri FO-5897J. Antibiot. (Tokyo)68(6)403-405(2015)
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Sartorypyrone A
20-O-Acetylsartorypyrone D
TN81351452396-10-9
Sartorypyrone A (20-O-Acetylsartorypyrone D) is a monocyclic sesquiterpene compound isolated from the soil fungus Neosartorya fischeri. This compound exhibits in vitro growth inhibitory activity against the MCF-7, NCI-H460, and A375-C5 cell lines, indicating its potential as an anticancer agent.
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