saralasin

Saralasin ([Sar1, Ala8] Angiotensin II) is an octapeptide derivative of angiotensin II. Saralasin acts as a competitive antagonist of the angiotensin II receptor, with a Ki value of 0.32 nM (occupying 74% of the binding sites), and also possesses partial agonist activity. Saralasin can be used in research on renovascular hypertension and renin-dependent (i.e., angiotensinogen-dependent) hypertension.

Saralasin TFA ([Sar1,Ala8] Angiotensin II) is a synthetic octapeptide analog of angiotensin II, functioning as a competitive antagonist at angiotensin II receptors with a K i value of 0.32 nM for 74% of its binding sites, while also exhibiting partial agonist activity. It is utilized in the study of renovascular and renin-dependent (angiotensinogenic) hypertension [1] [3] [6].

Saralasin acetate is a Non-selective angiotensin II antagonist.

Thr8-saralasin is an angiotensin antagonist.