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By Target- Apoptosis
- Protease-activated Receptor(1)
- Others(1)
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Results for "
rwj56110 dihydrochloride
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- RWJ-56110 dihydrochlorideT367172387505-58-8RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 μM), showing no effect on PAR-2, PAR-3, or PAR-4. It inhibits the aggregation of human platelets induced by SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), with high selectivity relative to U46619. RWJ-56110 dihydrochloride also blocks angiogenesis and the formation of new vessels in vivo, and induces cell apoptosis[1][2].
- $481
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