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Results for "
rpl-554
" in TargetMol Product Catalog- Inhibitors & Agonists2
(E/Z)-Ensifentrine
T69491298680-25-8
(E Z)-Ensifentrine is a potent and selective PDE3 4 inhibitor that acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and anti-inflammatory effects. It is being developed by Verona Pharma as a potential treatment for asthma and hay fever and is currently in clinical trials.
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Ensifentrine
Ensifentrinum, Ensifentrina
T253761884461-72-6
Ensifentrine (Ensifentrinum) is a PDE3 4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), that is under clinical development for the treatment of asthma and COPD and, potentially, cystic fibrosis.
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