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Results for "
rorgammat inverse agonist 10
" in TargetMol Product Catalog- Inhibitors & Agonists1
RORγt Inverse agonist 10
T400432413986-35-1
RORγt Inverse agonist 10 is a highly potent, orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits RORγt activity, a key transcription factor regulating genes linked to psoriasis pathogenesis, including [IL-17A], [IL-22], and [IL-23R].
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