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Results for "
roflumilast n-oxide
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Isotope Products1
Roflumilast N-oxide
T4462292135-78-5
Roflumilast N-oxide is an inhibitor of PDE type 4.
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Roflumilast N-Oxide-d4
TMIH-0502
Roflumilast N-Oxide-d4 is a deuterated compound of Roflumilast N-Oxide. Roflumilast N-Oxide has a CAS number of 292135-78-5. Roflumilast N-oxide is a PDE type 4 inhibitor.
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Roflumilast
BYK 20869, BY 217, B9302-107, APTA 2217
T1024162401-32-3
Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling.
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