rlh

RLH 033 is a selective ligand for the sigma 1 recognition site.

BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 96 nM, 23 nM, and 78 nM for hLH (human LH), rLH (rat LH), and cLH (cynomolgus monkey LH), respectively. It is the first nanomolar hLH-R antagonist that reduces sex hormone levels in vivo [1].

BAY-899 is an orally active and selective antagonist of the luteinizing hormone receptor (LH-R), with IC50 values of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH). In vivo studies have shown that BAY-899 effectively reduces sex hormone levels[1].

(R)-BAY-899 is an R-isomer of BAY-899. BAY-899 is a selective, orally active luteinizing hormone receptor (LH-R) antagonist that acts on hLH (human LH) (IC50: 185 nM) and rLH (rat LH) (IC50: 46 nM).