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Results for "
ritlecitinib tosylate
" in TargetMol Product Catalog- Inhibitors & Agonists1
Ritlecitinib tosylate
T698222192215-81-7
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.
- $198
Size
QTY
T605651792180-79-0
(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective JAK3 inhibitor with an IC50 of 144.8 nM[1].
- $113
Size
QTY
PF-06651600
T53821792180-81-4
Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor with an IC50 of 33.1 nM and does not affect the activity of JAK1/2.
- $39
Size
QTY
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