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ribociclib hydrochloride

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Ribociclib hydrochloride
LEE011 hydrochloride, LEE 011 hydrochloride
T157301211443-80-9
Ribociclib hydrochloride (LEE011 HCl) is a selective, orally active cyclin-dependent kinase CDK4/6 inhibitor (IC50=10/39 nM) that blocks cell cycle progression and inhibits tumor cell proliferation.
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Ribociclib-d6 hydrochloride
TMID-0398
Ribociclib-d6 (hydrochloride) is a deuterated form of Ribociclib, which is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and has over 1000-fold lower activity against the cyclin B/CDK1 complex.
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