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By Target- CCR
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Results for "
resolvin d5
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Natural Products1
- Resolvin D57(S),17(S)-diHDHAT37606578008-43-2Resolvin D5 is an oxidised lipid mediator derived from docosahexaenoic acid (DHA) with anti-inflammatory properties. It inhibits the production of interleukin-6 (IL-6) and chemokine CCL5 in LPS-stimulated THP-1 cells via the ERK-NF-κB signalling pathway.
- $555
SizeQTY - Resolvin D5 n-3 DPAT2146391609382-32-2Resolvin D5 n-3 DPA is a specific pro-resolving lipid mediator (SPM) derived from docosapentaenoic acid (DPA). It acts as an agonist for GPR101, GPR12, and GPR84 receptors, with EC50 values of 4.6 pM, 14 pM, and 1.5 pM, respectively. This compound exhibits potent pro-resolving and anti-inflammatory properties, reducing cell adhesion on TNF-α-activated human endothelial monolayers. It significantly enhances leukocyte-targeting activity by increasing the phagocytic capacity of neutrophils and macrophages to engulf bacteria. Resolvin D5 n-3 DPA is useful for studying intestinal inflammation.
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