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- Prostaglandin Receptor(1)
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By Target By ResearchField- Cancer(1)
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Results for "
rebamipide-d4
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- Isotope Products1
- Rebamipide-D4Rebamipide D4, Proamipide D4, OPC12759 D4T195471219409-06-9Rebamipide-D4 is deuterium labeled Rebamipide (T1562).
- $545
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- Rebamipide
Proamipide, OPC12759T156290098-04-7Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.- $33
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