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Results for "

rat lpa1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
  • Antibody Products
    2
    TargetMol | Antibody_Products
ASP6432
T143351282549-08-9
ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.
  • $297
8-10 weeks
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UCM-05194 ammonium
T211883
UCM-05194 (ammonium) is an agonist for the lysophosphatidic acid receptor 1 (LPA1). It induces calcium mobilization in RH7777 cells expressing LPA1, with an EC50 of 0.24 µM. In B103 rat neuroblastoma cells that overexpress LPA1, UCM-05194 (ammonium) promotes neurite retraction and cell migration. Additionally, it alleviates acetic acid-induced writhing and mechanical hyperalgesia in mice.
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ONO-0300302
ONO 0300302
T28245856689-51-5
ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, p.o.) and dog (1 mg/kg, p.o.) over
  • $2,200
3-6 months
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