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qrx431

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Sobetirome
IACS-010759, GC1, QRX-431, GC-1, GC 1
T5313211110-63-3
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
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IACS-010759
IACS-10759, IACS10759, IACS 10759
T53371570496-34-2
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
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TargetMol
IACS-010759 hydrochloride
IACS-10759 hydrochloride, IACS10759 hydrochloride, IACS-010759 HCl, IACS010759 HCl
T275681807523-99-4
IACS-010759 hydrochloride is an orally potent and selective OXPHOS inhibitor that inhibits proliferation and induces apoptosis in OXPHOS-dependent brain cancer and acute myeloid leukaemia models for the study of relapsed/refractory AML and advanced solid tumours.
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7-10 days
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