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By Target- AMPK
- Akt(1)
- COX(1)
- EGFR(1)
- IL Receptor(1)
- Lipoxygenase(1)
- mTOR(1)
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Results for "
qianghuo
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Natural Products2
Phenethyl ferulate
Caffeic Acid 3-Methyl Phenethyl Ester
TN233071835-85-3
Phenethyl ferulate (Caffeic Acid 3-Methyl Phenethyl Ester) has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane induced colon tumors. It shows inhibitory activity against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50 values of 4.35 μM and 5.75 μM, respectively.
- $54
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QTY
Isopropyl ferulate
TN178959831-94-6
Isopropyl ferulate is a bioactive compound from Rhizoma et Radix Notopterygii (Qianghuo) that exerts strong cytotoxic effects against PANC-1 human pancreatic cancer cells with a PC50 of 17.5 μg/mL, mechanistic analysis of Isopropyl ferulate via network pharmacology implicates Isopropyl ferulate regulate PI3K/Akt/mTOR, ErbB, and IL-17 pathways. Further validated in IMQ-induced and LPS-stimulated model systems, confirmed its significant modulation of PI3K/Akt/mTOR signaling, supporting the relevance of Isopropyl ferulate in cancer therapeutics.
- $40
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