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pyrocoll

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Pyrocoll
T35912484-73-1
Pyrocoll, a bacterial metabolite originally isolated from Streptomyces, inhibits the growth of A. aurescens, A. globiformis, A. oxydans, A. pascens, and R. erythropolis (MICs = 10, 1, 10, 3, and 10 μg ml, respectively), as well as HMO2, HepG2, and MCF-7 cancer cells (GI50s = 0.28, 0.42, and 2.2 μg ml, respectively) in vitro. Pyrocoll is also active against P. falciparum and T. rhodesiense (IC50s = 1.19 and 1.97 μg ml, respectively).
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