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px20606 trans racemate

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
PX20606 trans racemate
PX-102 trans racemate
T125831268244-85-4
PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).
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6-8 weeks
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TargetMol
PX20606
PX-102
T883531268245-19-7
PX20606 is an orally active farnesoid X receptor (FXR) agonist, demonstrating EC50 values of 220 nM (mFXR) and 50 nM (hFXR) in Gal4-FXR assays. It induces the expression of the tumor suppressor gene NDRG2 and inhibits tumor growth and metastasis in a mouse HCC model. Additionally, PX20606 exhibits hepatoprotective properties.
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10-14 weeks
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