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Results for "

px105684

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
  • Isotope Products
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    TargetMol | Isotope_Products
  • Rac-Belinostat
    PXD101, PX-105684, NSC726630
    T1852414864-00-9
    Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
    • $37
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  • Belinostat
    PXD-101, PXD101, PX105684
    T8517866323-14-0
    Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
    • $40
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    TargetMol | Citations Cited
  • Belinostat-d5
    PXD101-d5, PX105684-d5
    TMIT-03702130852-65-0
    Belinostat-d5 (PXD101-d5) is the deuterium-labeled form of Belinostat. Belinostat (PXD101; PX105684) acts as a potent HDAC inhibitor, with an IC50 of 27 nM in HeLa cell extracts.
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