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(2)
By Target- Hedgehog/Smoothened
- Apoptosis(1)
- Prostaglandin Receptor(1)
- Others(1)
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By Target By ResearchField- Cancer(1)
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Results for "
ptch1
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Peptide Products1
- Antibody Products1
- TriparanolNSC-65345, NSC65345, NSC 65345, MER-29T2629678-41-1In houseTriparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic toxicity.
- $298
SizeQTY - Prostaglandin E1 ethanolamideAlprostadil EthanolamideT84592210976-81-1Prostaglandin E1 ethanolamide, an analog of Prostaglandin E1 (PGE1), can potentially inhibit the GLI2-induced expression of target genes such as Gli1 and Ptch1, thereby reducing tumor growth [1].
- $149
SizeQTY - HL2-m5TP31022130846-15-8HL2-m5 is an inhibitor of the sonic hedgehog/patched (Shh/PTCH1) interaction, with a Kd for Shh of 170 nM. It effectively inhibits the activation of the Hedgehog signaling pathway and the transcription of Gli-controlled genes, with an IC50 of 230 nM.
- Inquiry Price
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