propiverine

Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).

Propiverine is a potent antimuscarinic agent that effectively inhibits cellular calcium influx, leading to the reduction of muscle spasm. It exhibits neurotropic and musculotropic effects specifically on the smooth muscles of the urinary bladder. Propiverine proves valuable in research concerning overactive bladder (OAB) [1] [2].

Propiverine N-oxide is the primary metabolite of propiverine hydrochloride, and it influences bladder contraction and saliva secretion in miniature pigs.

Propiverine N-oxide (hydrochloride) is the major metabolite of propiverine in human plasma or urine.