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propargyl-peg3-alcohol

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
  • PROTAC Products
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    TargetMol | PROTAC
Propargyl-PEG3-alcohol
T16606208827-90-1
Propargyl-PEG3-alcohol is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
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7-10 days
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L18I
T200405
L18I is a PROTAC (Proteolysis Targeting Chimera) that targets Btk to mitigate inflammation in autoimmune diseases. The components of L18I include the PROTAC target protein ligand IBT6A, the PROTAC linker Propargyl-PEG3-alcohol, and the E3 ubiquitin ligase ligand Lenalidomide-Br. Notably, the active control for the target protein ligand is IBT6A-CO-ethyne, while the conjugate of the E3 ubiquitin ligase ligand with the linker is Lenalidomide-C3-PEG3-N3.
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