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prima1

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  • Inhibitors & Agonists
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    TargetMol | All_Dye_Reagents
PRIMA-1
PRIMA 1, NSC-281668, 2,2-Bis(hydroxymethyl)-3-quinuclidinone
T69545608-24-2
PRIMA-1 (NSC-281668) is a mutant p53 reactivator that induces apoptosis and inhibits the growth of human tumors with mutant p53.
  • $47
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Eprenetapopt
PRIMA-1Met, APR-246
T44145291-32-7
Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.
  • $67
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