pnu100766

Linezolid (PNU-100766), the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and streptococcus. The drug takes effect as the inhibitor of the initiation of bacterial protein synthesis.

(R)-Linezolid, an impurity of Linezolid, inhibits the initiation of bacterial protein synthesis.

Linezolid-D3 is a deuterated analogue of linezolid (T0391) and can be used for isotope tracing. Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis. Linezolid-D3 can be used in antimicrobial pharmacokinetic and tracer-based biochemical studies to investigate the mechanisms of protein synthesis inhibition and to track the distribution of the antibiotic in bacterial translation models.

PNU-100766-D8 is a deuterium-labeled form of PNU-100766 (TMSM-3494). Linezolid (PNU-100766) is the first member of the oxazolidinone class of synthetic antibiotics, functioning by inhibiting the initiation of bacterial protein synthesis, thereby exhibiting anti-infective properties.