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piromelatine

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Piromelatine
NEU-P-11, NEU-P 11, NEU-P11
T34081946846-83-9
Piromelatine is an agonist of melatonin MT1 MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibitory effects on P2X3, TRPV1, and Nav1.7 channels, and can be used in studies of sleep-promoting, pain-relieving, anti-neurodegenerative, and antidepressant diseases. diseases, and can be used to improve memory deficits associated with chronic mild stress-induced lack of pleasure in rats.
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6-8 weeks
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