piperaquine

Piperaquine is a bis-quinoline antimalarial compound, a companion compound to artemisinin.Piperaquine is a component of Eurartesim, which is commonly used in the study of malaria infections.

Piperaquine tetraphosphate tetrahydrate is a potent anti-parasites agent.

Piperaquine tetraphosphate, a potent antimalarial agent, demonstrates inhibitory effects against both chloroquine-sensitive and chloroquine-resistant malaria isolates. When combined with dihydroartemisinin, it holds potential for researching chloroquine-resistant malaria [1] [2].

Piperaquine phosphate is an anti-malaria compound commonly used in combination with artemisinin to inhibit Plasmodium falciparum.

Antiparasitic agent-32 (compound M9) is an analogue of Piperaquine and acts as a potent antiparasitic agent targeting plasmodium falciparum lactate dehydrogenase (Pf LDH) with a Pf3D7IC50 of 0.40 μM. It demonstrates significant activity against both the asexual and gametocyte stages of plasmodium falciparum. Its antimalarial effect is achieved through stable and specific non-covalent interactions at the NADH binding site. Antiparasitic agent-32 is applicable in malaria research.