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Results for "
pf06260933 hcl
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- PF-06260933 HClPF-06260933 dihydrochloride, PF06260933 dihydrochloride, PF 06260933 dihydrochlorideT339451883548-86-4PF-06260933 Dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It can improve the fasting hyperglycemia in mice. In addition, it inhibited Mink and Tnik (IC50 values of 8 and 13 nM, respectively).
- $816
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- PF 06260933 dihydrochloride
T36016MAP4K4 (HGK) inhibitor (IC50 = 140 nM). Also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively). Improves fasting hyperglycemia in mice. Orally active. Ammirati et al (2015) Discovery of an in vivo tool to establish proof-of-concept for MAP4K4-based antidiabetic treatment. ACS Med.Chem.Lett. 6 1128 PMID:26617966- $271
SizeQTY - PF-06260933PF-6260933, PF6260933, PF 6260933T42211811510-56-1PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.
- $42
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