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(2)
By Target- Apoptosis
- PAK(2)
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Results for "
pf03758309
" in TargetMol Product Catalog- Inhibitors & Agonists2
PF-3758309
PF-309, PF-03758309, PF 3758309
T6626898044-15-0
PF-3758309 (PF-03758309) (IC50=1.3 nM), a pyrrolopyrazole inhibitor of PAK4, has effective ATP-competition.
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PF-3758309 hydrochloride
PF-03758309 hydrochloride
T42301279034-84-2
PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hydrochloride binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
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