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Results for "
pf-06459988
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- PF-06459988T164921428774-45-1In housePF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor. PF-06459988 has high efficiency and high affinity for EGFRs double mutants containing T790M, and has minimal activity against WT EGFR. PF-06459988 makes a candidate drug for the treatment of cancer.
- $149
SizeQTY - (3S,4S)-PF-06459988T392991858291-14-1(3S, 4S)-PF-06459988 is the less active S enantiomer of PF-06459988, a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR), exhibiting excellent selectivity against EGFR wild-type due to its minimally reactive electrophile, reducing off-target labeling likelihood.
- $82
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