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pdgfrαv561d

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
TAK-593
T169751005780-62-0
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).
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Amuvatinib hydrochloride
MP470 hydrochloride, HPK 56 hydrochloride
T142821055986-67-8
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administered multi-targeted tyrosine kinase inhibitor effective against mutant forms of c-Kit, PDGFRα, Flt3, c-Met, and c-Ret, and it suppresses DNA repair by inhibiting the RAD51 protein, contributing to its antineoplastic activity[1][2][3][4].
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3-6 months
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