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Results for "
pde3a-slfn12 complex
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products1
bay 2666605
T98052275774-60-0
BAY 2666605 is an orally active inhibitor of PDE3A (IC50 = 87 nM) and PDE3B (IC50 = 50 nM) with noted anticancer effects.
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OPB-171775
T895552131210-15-4
OPB-171775 is a molecular glue that forms a ternary complex with phosphodiesterase 3A (PDE3A) and schlafen family member 12 (SLFN12). This compound induces cell death mediated by SLFN12 RNase, activates the SLFN12 RNase-associated GCN2 signaling pathway, and demonstrates antitumor activity.
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