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By Target- Cysteine Protease
- Proteasome(1)
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Results for "
pd151746
" in TargetMol Product Catalog- Inhibitors & Agonists1
PD 151746
T2493179461-52-0
PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0.03 μM (Ki for μ-calpain) and 5.33 ± 0.77 μM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2].
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