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(1)
By Target- Acyltransferase
- Cytochromes P450(1)
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Results for "
pd148515
" in TargetMol Product Catalog- Inhibitors & Agonists1
Avasimibe
PD-148515, CI-1011
T2753166518-60-1
Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9 1A2 2C19 (IC50: 2.9 13.9 26.5 μM).
- $43
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