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(2)
By Target- Cysteine Protease
- Proteasome(1)
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Results for "
pd 151746
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- PD 151746T2493179461-52-0PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0.03 μM (Ki for μ-calpain) and 5.33 ± 0.77 μM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2].
- $35
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- （Z)-PD151746(Z)-PD 151746T212903181765-30-0PD 151746 is a highly selective calpain inhibitor. Its inhibitory activity against μ-calpain (Ki=0.26±0.03 μM) is approximately 20-fold higher than that against m-calpain (Ki=5.33±0.77 μM).
- $46
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