paullone

Paullone is an inhibitor of cyclin-dependent kinases (CDKs). The CDKs are a family of protein kinases that are involved in regulation of the cell cycle.

SA 152 is an organophosphoric inhibitor.

KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp3 gene by enhancing TGFβ-Smad3 signaling pathway.

Cazpaullone is an inhibitor of glycogen synthase kinase-3 (GSK-3). It also shows transient stimulation of the mRNA expression of the beta cell transcription factor Pax4.

1-Azakenpaullone (azakenpaullone) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.

Alsterpaullone, 2-Cyanoethyl is a selective dual inhibitor of Cdk1/cyclin B and GSK-3β.

Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec