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oxotremorine m iodide

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Oxotremorine M iodide
Oxotremorine methiodide
T123393854-04-4
Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.
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6-8 weeks
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vu6019650
T73272
VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR ( IC 50 =36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA) [1] [2] .
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8-10 weeks
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