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osmi-1

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
OSMI-1
T164091681056-61-0In house
OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans.
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6-8 weeks
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TargetMol | Citations Cited
(Rac)-OSMI-1
T63988
(Rac)-OSMI-1 is a racemate of OSMI-1. OSMI-1 is an inhibitor of O-GlcNAc transferase (OGT) (IC50: 2.7 μM). OSMI-1 inhibits protein O-linked N-acetylglucosaminoglycans (O-GlcNAcylation) in mammalian cell lines and does not qualitatively alter cell surface N- or O-linked glycans.
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10-14 weeks
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PG 34
T638711681056-62-1
PG 34 is a structural analogue of OSMI-1 and a weak inhibitor of O-GlcNAc translocase (OGT) with an IC50 value of 68 μM.
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7-10 days
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