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Results for "
olodanrigan sodium
" in TargetMol Product Catalog- Inhibitors & Agonists1
Olodanrigan sodium
PD-126055 sodium, PD126055 sodium, EMA-401 sodium, EMA401 sodium
T282331316755-17-5
Olodanrigan sodium (EMA-401 sodium) is an orally active and selective angiotensin II type 2 receptor (AT2R) antagonist, which can be used in research on neurological diseases.
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PD-126055, EMA401
T44311316755-16-4
Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. EMA401 blocks p38, p42/p44 mitogen-activated protein kinase (MAPK) activation, neurite outgrowth in adult rat DRG neurons, and sensitization of adult rat and human DRG neurons induced by AngII. It inhibits capsaicin responses in cultured hDRG neurons.
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