oleic acid13c

Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 μg/ml. It also inhibits fMLF-induced neutrophil aggregation and degranulation by 55 and 68%, respectively, when used at a concentration of 5 μM, similar to arachidonic acid .3 Oleic acid (60 μM) induces release of intracellular calcium in human platelets.4

Palmitoleic acid-13C16 is a 13C-labeled variant of Palmitoleic acid. As a constituent of fatty acids, Palmitoleic acid helps prevent death caused by cerebrovascular diseases in SHRSP rats.

Linoleic acid-13C1 is a 13C-labeled form of linoleic acid, a widely found polyunsaturated fatty acid (PUFA) present in plant oils, nuts, and seeds. As a component of membrane phospholipids, linoleic acid contributes to membrane fluidity and supports the transdermal water barrier of the epidermis. Its oxidation can lead to the damage of red blood cells and hemoglobin.

Oleic acid-13C18 is the 13C-labeled version of oleic acid. Oleic acid (9-cis-Octadecenoic acid) is the most prevalent monounsaturated fatty acid found in human adipose tissue and other tissues. It acts as an activator of the Na+/K+ATPase enzyme.