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(2)
By Target- Apoptosis
- PLK(2)
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- GPR
- LHRH
- Opioid Receptor
- Oxytocin Receptor
- RAAS
- Reductase
- Thyroid hormone receptor(THR)
- 5-HT Receptor
- Adenosine Receptor
- Adiponectin receptor
- Adrenergic Receptor
- Amylin Receptor
- Annexin A
- Apelin receptor
- Arrestin
- Bombesin Receptor
- Bradykinin Receptor
- cAMP
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- CRFR
- CXCR
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- Sigma receptor
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- AhR
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- CCR
- CD38
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- Complement System
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- Cytokine release
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- Interleukin
- IRAK
- LTR
- MALT
- MRP
- MyD88
- NADPH-oxidase
- NO Synthase
- NOD
- NOD-like Receptor (NLR)
- NOS
- Nrf2
- PD-1/PD-L1
- PGE Synthase
- Prostaglandin Receptor
- Pyroptosis
- Reactive Oxygen Species
- ROS
- STING
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- Hydrolases,EC 3
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By Target By ResearchField- Cancer(1)
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Results for "
ocifisertib
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Ocifisertib(CFI-400945 free base)T73841338806-73-7Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4 (PLK4; Ki value 0.26 nM; IC50 value 2.8 nM).
- $38
SizeQTY - Ocifisertib hydrochlorideCFI-400945 hydrochlorideT2030661338799-83-9Ocifisertib hydrochloride (CFI-400945 hydrochloride) is the hydrochloride salt form of Ocifisertib. It is an orally bioavailable PLK4 inhibitor with a Ki of 0.26 nM and an IC50 of 2.8 nM. This compound inhibits the growth of multiple cancer cell types, causes cell cycle arrest at the G2/M phase, and induces apoptosis. In mouse models, Ocifisertib hydrochloride exhibits antitumor activity.
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