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Results for "
ocifisertib
" in TargetMol Product Catalog- Inhibitors & Agonists2
ocifisertib(cfi-400945 free base)
T73841338806-73-7
Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4 (PLK4; Ki value 0.26 nM; IC50 value 2.8 nM).
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Ocifisertib hydrochloride
CFI-400945 hydrochloride
T2030661338799-83-9
Ocifisertib hydrochloride (CFI-400945 hydrochloride) is the hydrochloride salt form of Ocifisertib. It is an orally bioavailable PLK4 inhibitor with a Ki of 0.26 nM and an IC50 of 2.8 nM. This compound inhibits the growth of multiple cancer cell types, causes cell cycle arrest at the G2 M phase, and induces apoptosis. In mouse models, Ocifisertib hydrochloride exhibits antitumor activity.
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