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By Target- Antifungal
- Apoptosis(1)
- Caspase(1)
- IGF-1R(1)
- NO Synthase(1)
- STAT(1)
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Results for "
nt-157
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Antifungal agent 157T2188912446130-20-5Antifungalagent 157 (Ex.I-339) is a heterocyclic pyrazine compound and a plant pathogen control agent, suitable for research related to plant pathogen infections.
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SizeQTY - Anticancer agent 157T78855Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 μg/mL, exhibiting both anti-inflammatory and anticancer effects. It interacts with inducible NO synthase (iNOS) and caspase 8, which facilitates apoptosis through nuclear fragmentation and chromatin condensation. Additionally, Anticancer Agent 157 effectively inhibits HT29 colon cancer cells (IC50 =2.45 μg/mL), Hep-G2 liver cancer cells (IC50 =3.25 μg/mL), and B16-F10 murine melanoma cells (IC50 =3.84 μg/mL) [1].
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