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By Target- Acetyl-CoA Carboxylase
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Results for "
nsc170984
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- PF-05221304STAT5 Inhibitor III, R 6238,, NSC 170984, ClesacostatT92091370448-25-1PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
- $86
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- Clesacostat tromethamine
QF09CQF4SR, PF-05221304 tromethamineT2027452334472-62-5Clesacostat (PF-05221304) is a potent and selective ACC inhibitor, with hACC1 IC50 of 13 nM and hACC2 IC50 of 9 nM. In animal models, PF-05221304 specifically inhibits hepatic DNL and demonstrates a significant safety margin for thrombocytopenia in non-human primate models.- Inquiry Price
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